News
Added Aug 31, 2018 -“The Magic of Muscadines” – Article from Winston-Salem Monthly, August 2018. By Kathy Norcross Watts. Read Article (.pdf)
Added October 8, 2011 – John Hopkins University Clinical Trial – Effects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Therapy for Prostate Cancer. Read Article (external link)
Added May 24, 2018 – John Hopkins University Clinical Trial – Effects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Therapy for Prostate Cancer. Read Article (external link)
Added April 19, 2009 -Muscadine Grape Skin Dietary Supplement Protects against Cancer Therapy Radiation Side Effects – Writeup by Dr. Ronald Carsten.*** Read Article (.pdf)
***The data (abstract) can be found by clicking here.
Added February 11, 2009 -Natural Sources of Resveratrol and Mechanisms of Action with Emphasis on Cardiovascular Disease: A Brief Review Read Article (.pdf)
Research
Selected Published Research on Health and Muscadine Grapes
- Paller CJ, Rudek, MA, Zhou XC, Wagner WD, Hudson TS, Anders N, Hammers HJ, Dowling D, King S, Antonarakis ES, Drake CG, Eisenberger MA, Denmeade SR, Rosner GL, Carducci MA. A phase I study of muscadine grape skin extract in men with biochemically recurrent prostate cancer: safety, tolerability, and dose determination. Prostate. 2015:75(14);1518-1520. DOI: 10.1158/1078-0432.CCR-17-1100
- Paller CJ, Zhou XXC, Heath E, Taplin ME, Mayer TM, Stein MN, Bubley GJ, Pili R, Hudson TS, Kakarla R, Abbas M, Anders N, Dowling D, King S, Bruns AB, Wagner WD, Drake CG, Antonarakis ES, Eisenberger MA, Denmeade SR, Rudek MA, Rosner GL, Carducci MA. Muscadine Grape Skin Extract in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trail. Clinical Cancer Research. 2018:24(2); 306-315. DOI: 10.1158/1078-0432.CCR-17-1100
- Ignacio DN, Mason KD, Hackett-Morton EC, Albanese C, Ringer L, Wagner WD, Wang PC, Carducci MA, Kachhap SK, Paller CJ, Mendonca J, Li-Ying Chan L, Lin B, Hartle DK, Green JE, Brown CA, Hudson TS. Muscadine grape skin extract inhibits prostate cancer cells by inducing cell-cycle arrest, and decreasing migration through heat shock protein 40. Heliyon. 2019 Jan 16;5(1):e01128. DOI: 10.1016/j.heliyon.2019.e01128
- Carsten RE, Bachand SM, Bailey SM, Le, PN, Robert N, Ullrich, RL Resveratrol and muscadine grape extract reduce radiation-induced bone marrow PU.1 gene loss and chromosome aberration frequency Cancer research annual meeting abstract 2009.