What is Resveratrol?


What is Piceatannol?




Resveratrol is a substance produced by several plants that has been studied for its health benefits, particularly in recent months. It first came to the attention of the scientific community as the possible explanation for the “French Paradox” – the relatively low incidences of heart disease despite a high dietary intake of saturated fats in a study conducted in Southern France. Recent studies suggest that resveratrol has estrogenic, cardioprotective and anticancer activities [1] [2] [3] [4] [5] [6] [7] [8].

Resveratrol is a naturally occurring compound present in many fruits, vegetables and wine. It is typically associated with extracts because most fruits (even vinifera grapes) have such small amounts of the compound, that extract methods are the only viable solution to retrieve measurable amounts. One of the highest sources of natural resveratrol is the skins of grapes, particularly the thick skins of the Muscadine grapes. The trans- and cis-resveratrol configurations are measurable in the muscadine grape skins.

The amount of resveratrol in muscadine grapes varies by cultivar and growing conditions. Muscadine Naturals uses a unique, chemical-free process that maintains the high level of natural antioxidants found in the fresh fruit. The dried fruit powders are blended for consistency.

The number of studies being conducted about resveratrol has grown at a rapid pace since 2000. In recent months, research has emerged on its life-extending potential due to its apparent ability to mimic calorie restriction (CR) in some laboratory animals. Some of the news associated with these studies suggests large amounts of resveratrol are needed. However, for the purpose of contributing to antioxidant effects, 2-4mg of resveratrol have been studied as providing an effect [2]. Another study suggests that a low amount of resveratrol is more effective than a higher amount [9]. Other studies suggests that the presence of flavanoids in products containing resveratrol may improve the bio-availability of the resveratrol [10] [11]. Muscadine Naturals products contain natural flavanoids (quercetin, myricein, kaempferol) as found in the fresh fruit, possibility enhancing
The bio-availability of the resveratrol. As research continues, more exciting health benefits of resveratrol are sure to be revealed.

For more studies on resveratrol and other phytonutrients, go to www.PubMed.com and key in any of the above phytonutrients along with the word antioxidant to find scientific studies that have been conducted all over the world. You can also add the word “muscadine” to seek specific studies that have been published about the muscadine grape.



Piceatannol is a natural stilbene occurring in a number of plant species, and it has been shown to have beneficial effects on human health. The compound can seldom be consumed by humans, because it occurs mostly in non-food plants, or in non-edible organs. There are only a few plants reported to contain minute amounts of piceatannol. The scarcity of this compound impedes researchers from continuing to study its properties and health benefits.

Piceatannol has a very similar structure to the renowned resveratrol and, also, similar anti-inflammatory and antioxidant properties. However, piceatannol has much more potent biological activity and bioavailability than resveratrol. Like resveratrol, piceatannol has been studied for its anti-cancer properties and has been deemed the superior agent of the two.

It has recently been discovered that the Muscadine grapes, along with our Muscadine grape products, contain piceatannol.

Our inventory of Muscadine grape skins, containing both resveratrol and piceatannol, is the largest known supply in the world. Our company has plans to upkeep and increase the supply of the Muscadine grapes so that we can continue to give you the 100% all-natural products you need for your health and happiness.

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